The Deep South Self Drive Holidays
Holiday in the Deep South region of Arkansas, Louisiana, Mississippi, Kentucky, Tennessee, Alabama, Georgia, North & South Carolina
The Deep South is a region of soul-stirring music, rich history, and breathtaking natural beauty, making it an unforgettable destination for your next holiday. Explore the Appalachian Mountains and take a scenic drive along the Blue Ridge Parkway, where rolling peaks, lush forests, and charming mountain towns create a picture-perfect backdrop. In Tennessee, immerse yourself in the heart of country music in Nashville, where the legendary Grand Ole Opry and honky-tonk bars fill the air with live tunes. Travel to Memphis, home of Elvis Presley’s Graceland, the birthplace of blues, and the famous Beale Street for an electrifying night out.
For those craving vibrant city life and deep cultural heritage, New Orleans in Louisiana is a must-visit. The lively French Quarter, known for its jazz clubs, Creole cuisine, and historic charm, sets the stage for an unforgettable experience. Head down to Mississippi, where blues music echoes through the Delta, or explore the antebellum mansions and Civil Rights history of Alabama and Georgia. In Kentucky, sip on world-famous bourbon along the Kentucky Bourbon Trail, or cheer on the thrill of the Kentucky Derby in Louisville.
Whether you’re looking for a road trip packed with history and culture or an adventure through the South’s stunning landscapes, this region has something for everyone. From the mountain beauty of the Carolinas to the sandy shores of the Gulf Coast, the Deep South is as diverse as it is captivating.
Can’t decide on the perfect route? No problem—Our UK based Travel Experts will craft a tailor-made road trip just for you, ensuring you experience the very best of this incredible region.
Why Route 66 through us?
We’re not just another tour operator offering Route 66 holidays. We know the road, the people, the buildings and the experience. We’re passionate about America's “Mother Road”… and once you’ve driven it, you will be too.
Historic Accommodation
We want you to experience the real feel of Route 66 and you’ll stay in restored historic hotels and motels in some locations. Should you prefer modern hotels we are happy to swap these for you.
Authentic Experience
Route 66 is not about driving on the interstate, it is about taking your time on the original route. We’ll tell you the best way to enjoy the trip by stopping at the best locations, diners and museums
We give back to Route 66
We’re active members of several state Route 66 associations and try to help those businesses which make the trip so special. You can help too by eating in a family run diner instead of a burger chain
Blues Highway
Bucket List!
After a couple of days enjoying Nashville, known as "Music City", you’ll follow the Blues Highway south through Memphis, Clarksdale and Vicksburg. Explore the delta blues music and the culture of the Deep South finishing your holiday in amazing New Orleans
11 nights from £1,999pp
including flights
Honky Tonk Highway
New for 2026!
Inspired by Rob Brydon’s Honky Tonk Road Trip, this 14-night self-drive holiday traces country music’s story from Nashville to Kentucky, the Smoky Mountains, Hank Williams’ Alabama and Elvis Presley’s Graceland before returning to Music City.
13 nights from £2,199pp
including flights
Deep South Loop
Updated for 2026
Experience the heart and soul of America’s Deep South on this 13-night self-drive holiday from Atlanta. Explore The Great Smoky Mountains, Nashville, Memphis, and New Orleans, tracing the roots of country, blues, and jazz across five southern states.
13 nights from £2,299pp
including flights
Country Roads, Mountains & Nashville
Bucket List!
Experience America’s most scenic drives on this 13-night self-drive holiday from Washington DC to Nashville. Follow the Skyline Drive and Blue Ridge Parkway through Shenandoah, the Smoky Mountains, and the Appalachian heartland to Music City, USA.
13 nights from £2,399pp
including flights
Time of your Life
Limited Time Only
Relive movie magic on this 11-night self-drive holiday visiting Dirty Dancing film locations, Dollywood (tickets included), and Nashville. Stay in the real “Kellerman’s,” explore the Blue Ridge Mountains, and enjoy live music and southern charm in Music City, USA.
11 nights or more from £2,449pp
including flights
Mountains & Coast
Limited Time Only
Spend several days in the Blue Ridge Mountains exploring the Great Smoky Mountains and driving the Blue Ridge Parkway before a leisurely tour through Atlanta, Savannah, Hilton Head Island, Charleston and Charlotte.
14 nights from £2,599pp
including flights
Austin to New Orleans
Limited Time Only
Begin your holiday in Austin, before heading south to San Antonio, site of the Alamo then onto to Houston, Lake Charles and finally New Orleans where you’ll stay in the famous French Quarter and enjoy their food, architecture, music and culture
12 nights from £2,049pp
including flights
Speak to a Travel Expert
Our team have travelled extensively across the USA & Canada to ensure that they can give first hand, unrivalled experience when discussing our holidays.
Call: 01234 938066Enquire NowBook Virtual AppointmentWhy choose RouteTrip USA?
Clients rate us 5/5 through Feefo
We’re multi-award winners
Your trip is fully ATOL Protected
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